Lisa Murkowski in 2022 AK Senate race

On Government Reform: Supported Brett Kavanaugh's confirmation to Supreme Court

"I can see 2022 from my house," Sarah Palin tweeted, mentioning Murkowski. The tweet was widely viewed as a thinly-veiled threat to challenge Murkowski in her 2022 reelection campaign to the Senate. "From my house" references a 2008 SNL sketch mocking Palin..

Murkowski was the only Republican to vote against a procedural move advancing Kavanaugh's nomination. "I believe that Brett Kavanaugh is a good man. But in my view he's not the right man for the court at this time," she said after the vote. "This has truly been the most difficult evaluation of a decision that I've ever had to make."

This isn't the first time Murkowski has faced the potential consequences of her votes. She lost the Republican primary to a Tea Party challenger in 2010, winning re-election with a write-in campaign instead.

On Government Reform: Ensure states can provide security for their elections

SEN. JOE MANCHIN (D-WV): What we're looking at is now, how do we protect what happened in the insurrection, that will never happen again, such as that people think they can come here and overturn it, but, on the other hand, how do we protect election workers with the federal crimes if someone threatens them or intimidates them or interferes with the election?

On Principles & Values: Bipartisanship: a good-faith effort to listen to one another

MURKOWSKI: It came about because you had a small group of people that said, we need to get something done, rather than just send a message. There was a good-faith effort to work through the hard things. Sometimes, when the going gets tough we retreat to the party messages. We listened to one another, gained an understanding, and said, the country needs this.

On Principles & Values: When the party says something wrong, I'll speak the truth