Lisa Murkowski in Twitter.com election tweets

On Government Reform: Supported Brett Kavanaugh's confirmation to Supreme Court

"I can see 2022 from my house," Sarah Palin tweeted, mentioning Murkowski. The tweet was widely viewed as a thinly-veiled threat to challenge Murkowski in her 2022 reelection campaign to the Senate. "From my house" references a 2008 SNL sketch mocking Palin..

Murkowski was the only Republican to vote against a procedural move advancing Kavanaugh's nomination. "I believe that Brett Kavanaugh is a good man. But in my view he's not the right man for the court at this time," she said after the vote. "This has truly been the most difficult evaluation of a decision that I've ever had to make."

This isn't the first time Murkowski has faced the potential consequences of her votes. She lost the Republican primary to a Tea Party challenger in 2010, winning re-election with a write-in campaign instead.